NUF2 (NM_145697) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]
Synonyms
CDCA1; CT106; NUF2R
Gene ID
83540
UniProt
Q9BZD4
Accession Number mRNA
NM_145697
Chromosomal Location
1q23.3
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome
Molecular Weight
54.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NUF2
Species
Human
Protein ID
NP_663735
Overview
Purified recombinant protein of Human NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) (NUF2), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/83540
Uniprot URL
https://www.uniprot.org/uniprot/Q9BZD4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_145697
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_663735
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