CABLES1 (NM_138375) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127) .Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Overview
Purified recombinant protein of Human Cdk5 and Abl enzyme substrate 1 (CABLES1), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
CABL1; CABLES; HsT2563; IK3-1
Gene ID
91768
UniProt
Q8TDN4, A0A024RC20
Accession Number mRNA
NM_138375
Chromosomal Location
18q11.2
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Molecular Weight
41.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CABLES1
Species
Human
Protein ID
NP_612384
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/91768
Uniprot URL
https://www.uniprot.org/uniprot/Q8TDN4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_138375
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_612384
Frequently Asked Questions
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