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SLC25A13 (NM_014251) Human Recombinant Protein

Product Specifications

Background

This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca (2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

Overview

Purified recombinant protein of Human solute carrier family 25, member 13 (citrin) (SLC25A13), nuclear gene encoding mitochondrial protein, transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

ARALAR2; CITRIN; CTLN2; NICCD

Gene ID

10165

UniProt

Q9UJS0

Accession Number mRNA

NM_014251

Chromosomal Location

7q21.3

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Druggable Genome

Molecular Weight

74 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SLC25A13

Species

Human

Protein ID

NP_055066

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/10165

Uniprot URL

https://www.uniprot.org/uniprot/Q9UJS0

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_014251

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_055066

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