JDP2 (NM_001135047) Human Recombinant Protein
Product Specifications
Background
Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.[UniProtKB/Swiss-Prot Function]
Synonyms
JUNDM2
Gene ID
122953
UniProt
Q8WYK2, A0A024R6D7
Accession Number mRNA
NM_001135047
Chromosomal Location
14q24.3
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Transcription Factors
Molecular Weight
18.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
JDP2
Species
Human
Protein ID
NP_001128519
Overview
Purified recombinant protein of Human Jun dimerization protein 2 (JDP2), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/122953
Uniprot URL
https://www.uniprot.org/uniprot/Q8WYK2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001135047
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001128519
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