JDP2 (NM_001135047) Human Recombinant Protein

Product Specifications

Background

Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Human Jun dimerization protein 2 (JDP2), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

JUNDM2

Gene ID

122953

UniProt

Q8WYK2, A0A024R6D7

Accession Number mRNA

NM_001135047

Chromosomal Location

14q24.3

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Transcription Factors

Molecular Weight

18.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.