Host cell factor C1 regulator 1 (HCFC1R1) (NM_001002018) Human Recombinant Protein
Product Specifications
Background
Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Human host cell factor C1 regulator 1 (XPO1 dependent) (HCFC1R1), transcript variant 3, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
HPIP
Gene ID
54985
UniProt
Q9NWW0
Accession Number mRNA
NM_001002018
Chromosomal Location
16p13.3
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome
Molecular Weight
15.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HCFC1R1
Species
Human
Protein ID
NP_001002018
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/54985
Uniprot URL
https://www.uniprot.org/uniprot/Q9NWW0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001002018
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001002018
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