C12orf32 (NM_031465) Human Recombinant Protein

Product Specifications

Background

Plays a role in DNA damage response (DDR) signaling upon genotoxic stresses such as ionizing radiation (IR) during the S phase. Recruited to sites of DNA damage through interaction with the 9-1-1 cell-cycle checkpoint response complex and TOPBP1 in a ATR-dependent manner. Required for the progression of the G1 to S phase transition. Plays a role in the stimulation of CHEK1 phosphorylation.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Human chromosome 12 open reading frame 32 (C12orf32), full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

Chromosome 12 open reading frame 32; HKMT1188; HKMT1188, MGC13204; MGC13204

Gene ID

83695

UniProt

Q9BSD3

Accession Number mRNA

NM_031465

Chromosomal Location

12p13.33

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Molecular Weight

26.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.