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IL17B (NM_014443) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. Alternative splicing results in multiple splice variants. [provided by RefSeq, Dec 2015]

Overview

Purified recombinant protein of Human interleukin 17B (IL17B), full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

IL-17B; IL-20; NIRF; ZCYTO7

Gene ID

27190

UniProt

Q9UHF5

Accession Number mRNA

NM_014443

Chromosomal Location

5q32

Expression System

E. coli

Tag

N-His

Related Pathways

Cytokine-cytokine receptor interaction

Field of Research

Cytokine-cytokine receptor interaction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Druggable Genome, Secreted Protein

Molecular Weight

18.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

IL17B

Species

Human

Protein ID

NP_055258

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/27190

Uniprot URL

https://www.uniprot.org/uniprot/Q9UHF5

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_014443

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_055258

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