IL17B (NM_014443) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. Alternative splicing results in multiple splice variants. [provided by RefSeq, Dec 2015]
Overview
Purified recombinant protein of Human interleukin 17B (IL17B), full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
IL-17B; IL-20; NIRF; ZCYTO7
Gene ID
27190
UniProt
Q9UHF5
Accession Number mRNA
NM_014443
Chromosomal Location
5q32
Expression System
E. coli
Tag
N-His
Related Pathways
Cytokine-cytokine receptor interaction
Field of Research
Cytokine-cytokine receptor interaction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome, Secreted Protein
Molecular Weight
18.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
IL17B
Species
Human
Protein ID
NP_055258
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/27190
Uniprot URL
https://www.uniprot.org/uniprot/Q9UHF5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014443
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055258
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