PLAGL1 (NM_001080955) Human Recombinant Protein
Product Specifications
Background
This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM) . Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues. [provided by RefSeq, Nov 2015]
Synonyms
LOT1; ZAC; ZAC1
Gene ID
5325
UniProt
Q9UM63, A1YLA2, Q9UM63-2
Accession Number mRNA
NM_001080955
Chromosomal Location
6q24.2
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, pH8.0, 500mM NaCl, 10% glycerol.
Function
Transcription Factors
Molecular Weight
44.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PLAGL1
Species
Human
Protein ID
NP_001074424
Overview
Purified recombinant protein of Human pleiomorphic adenoma gene-like 1 (PLAGL1), transcript variant 7, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5325
Uniprot URL
https://www.uniprot.org/uniprot/Q9UM63
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001080955
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001074424
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
