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TFEC (NM_001018058) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

Overview

Purified recombinant protein of Human transcription factor EC (TFEC), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

BHLHe34; hTFEC-L; TCFEC; TFE-C; TFEC-L; TFECL

Gene ID

22797

UniProt

O14948

Accession Number mRNA

NM_001018058

Chromosomal Location

7q31.2

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Druggable Genome, Transcription Factors

Molecular Weight

35.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

TFEC

Species

Human

Protein ID

NP_001018068

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/22797

Uniprot URL

https://www.uniprot.org/uniprot/O14948

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001018058

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001018068

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