TFEC (NM_001018058) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Overview
Purified recombinant protein of Human transcription factor EC (TFEC), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
BHLHe34; hTFEC-L; TCFEC; TFE-C; TFEC-L; TFECL
Gene ID
22797
UniProt
O14948
Accession Number mRNA
NM_001018058
Chromosomal Location
7q31.2
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome, Transcription Factors
Molecular Weight
35.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TFEC
Species
Human
Protein ID
NP_001018068
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/22797
Uniprot URL
https://www.uniprot.org/uniprot/O14948
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001018058
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001018068
Frequently Asked Questions
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