CITED2 (NM_006079) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Overview
Purified recombinant protein of Human Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (CITED2), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
ASD8; MRG-1; MRG1; P35SRJ; VSD2
Gene ID
10370
UniProt
Q99967, D9ZGF1
Accession Number mRNA
NM_006079
Chromosomal Location
6q24.1
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome, Transcription Factors
Molecular Weight
28.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CITED2
Species
Human
Protein ID
NP_006070
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10370
Uniprot URL
https://www.uniprot.org/uniprot/Q99967
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006079
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006070
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