MARK2 (NM_017490) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]
Synonyms
EMK-1; EMK1; PAR-1; Par-1b; Par1b
Gene ID
2011
UniProt
Q7KZI7, A8K2S4
Accession Number mRNA
NM_017490
Chromosomal Location
11q13.1
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome, Protein Kinase
Molecular Weight
82.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MARK2
Species
Human
Protein ID
NP_059672
Overview
Purified recombinant protein of Human MAP/microtubule affinity-regulating kinase 2 (MARK2), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2011
Uniprot URL
https://www.uniprot.org/uniprot/Q7KZI7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_017490
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_059672
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