MARK2 (NM_017490) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]

Overview

Purified recombinant protein of Human MAP/microtubule affinity-regulating kinase 2 (MARK2), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

EMK-1; EMK1; PAR-1; Par-1b; Par1b

Gene ID

2011

UniProt

Q7KZI7, A8K2S4

Accession Number mRNA

NM_017490

Chromosomal Location

11q13.1

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Druggable Genome, Protein Kinase

Molecular Weight

82.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.