OASL (NM_003733) Human Recombinant Protein
Product Specifications
Background
Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.[UniProtKB/Swiss-Prot Function]
Synonyms
OASL1; OASLd; p59 OASL; p59-OASL; p59OASL; TRIP-14; TRIP14
Gene ID
8638
UniProt
Q15646
Accession Number mRNA
NM_003733
Chromosomal Location
12q24.31
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0
Function
Druggable Genome
Molecular Weight
59 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
OASL
Species
Human
Protein ID
NP_003724
Overview
Purified recombinant protein of Human 2'-5'-oligoadenylate synthetase-like (OASL), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8638
Uniprot URL
https://www.uniprot.org/uniprot/Q15646
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003733
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003724
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