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OASL (NM_003733) Human Recombinant Protein

Product Specifications

Background

Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Human 2'-5'-oligoadenylate synthetase-like (OASL), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

OASL1; OASLd; p59 OASL; p59-OASL; p59OASL; TRIP-14; TRIP14

Gene ID

8638

UniProt

Q15646

Accession Number mRNA

NM_003733

Chromosomal Location

12q24.31

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0

Function

Druggable Genome

Molecular Weight

59 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

OASL

Species

Human

Protein ID

NP_003724

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/8638

Uniprot URL

https://www.uniprot.org/uniprot/Q15646

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003733

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003724

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