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MAD2L1 binding protein (MAD2L1BP) (NM_001003690) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1) . MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Synonyms

CMT2

Gene ID

9587

UniProt

Q15013

Accession Number mRNA

NM_001003690

Chromosomal Location

6p21.1

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0

Function

Druggable Genome

Molecular Weight

34.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

MAD2L1BP

Species

Human

Protein ID

NP_001003690

Overview

Purified recombinant protein of Human MAD2L1 binding protein (MAD2L1BP), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9587

Uniprot URL

https://www.uniprot.org/uniprot/Q15013

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001003690

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001003690

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