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NKD2 (NM_033120) Human Recombinant Protein

Selected Variant

PH31436E1

Size: 50 µg

Product Specifications

Background

This gene encodes a member of a family of proteins that function as negative regulators of Wnt receptor signaling through interaction with Dishevelled family members. The encoded protein participates in the delivery of transforming growth factor alpha-containing vesicles to the cell membrane. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]

Overview

Purified recombinant protein of Human naked cuticle homolog 2 (Drosophila) (NKD2), full length, with N-terminal HIS tag, expressed in E.coli, 50ug

Synonyms

Naked2

Gene ID

85409

UniProt

Q969F2

Accession Number mRNA

NM_033120

Chromosomal Location

5p15.33

Expression System

E. coli

Tag

N-His

Related Pathways

Wnt signaling pathway

Field of Research

Wnt signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Druggable Genome

Molecular Weight

49.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

NKD2

Species

Human

Protein ID

NP_149111

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/85409

Uniprot URL

https://www.uniprot.org/uniprot/Q969F2

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_033120

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_149111

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