KLF5 (NM_001730) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
Overview
Purified recombinant protein of Human Kruppel-like factor 5 (intestinal) (KLF5), full length, with N-terminal HIS tag, expressed in E.coli, 50ug
Synonyms
BTEB2; CKLF; IKLF
Gene ID
688
UniProt
Q13887, Q5T6X2
Accession Number mRNA
NM_001730
Chromosomal Location
13q22.1
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors
Molecular Weight
50.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KLF5
Species
Human
Protein ID
NP_001721
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/688
Uniprot URL
https://www.uniprot.org/uniprot/Q13887
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001730
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001721
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