BOLA3 (NM_001035505) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that plays an essential role in the production of iron-sulfur (Fe-S) clusters for the normal maturation of lipoate-containing 2-oxoacid dehydrogenases, and for the assembly of the mitochondrial respiratory chain complexes. Mutation in this gene has been associated with multiple mitochondrial dysfunctions syndrome-2. Two alternatively spliced transcript variants encoding different isoforms with distinct subcellular localization have been reported for this gene (PMID:21944046) . [provided by RefSeq, Dec 2011]
Synonyms
MMDS2
Gene ID
388962
UniProt
Q53S33, Q8N338
Accession Number mRNA
NM_001035505
Chromosomal Location
2p13.1
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Transcription Factors
Molecular Weight
11.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
BOLA3
Species
Human
Protein ID
NP_001030582
Overview
Purified recombinant protein of Human bolA homolog 3 (E. coli) (BOLA3), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/388962
Uniprot URL
https://www.uniprot.org/uniprot/Q53S33
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001035505
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001030582
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
