BOLA3 (NM_001035505) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein that plays an essential role in the production of iron-sulfur (Fe-S) clusters for the normal maturation of lipoate-containing 2-oxoacid dehydrogenases, and for the assembly of the mitochondrial respiratory chain complexes. Mutation in this gene has been associated with multiple mitochondrial dysfunctions syndrome-2. Two alternatively spliced transcript variants encoding different isoforms with distinct subcellular localization have been reported for this gene (PMID:21944046) . [provided by RefSeq, Dec 2011]

Overview

Purified recombinant protein of Human bolA homolog 3 (E. coli) (BOLA3), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.coli, 50ug

Synonyms

MMDS2

Gene ID

388962

UniProt

Q53S33, Q8N338

Accession Number mRNA

NM_001035505

Chromosomal Location

2p13.1

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Transcription Factors

Molecular Weight

11.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.