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PTPN20A (NM_001042389) Human Recombinant Protein

Product Specifications

Background

The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes and several are mutated in human diseases. Chromosome 10q contains a segmental duplication resulting in multiple copies of the protein tyrosine phosphatase, non-receptor type 20 gene. The two nearly identical copies are designated as PTPN20A and PTPN20B. A third copy is only partially duplicated and contains a pseudogene, designated as PTPN20C. This gene encodes the more centromeric copy, PTPN20A. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human protein tyrosine phosphatase, non-receptor type 20A (PTPN20A), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.coli, 50ug

Synonyms

BA142I17.1; CT126; hPTPN20; PTPN20B

Gene ID

653129

Accession Number mRNA

NM_001042389

Chromosomal Location

10q11.22

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Druggable Genome

Molecular Weight

48.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PTPN20A

Species

Human

Protein ID

NP_001035848

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/653129

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001042389

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001035848

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