PPP2R3B (NM_013239) Human Recombinant Protein
Product Specifications
Background
Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. [provided by RefSeq, Apr 2010]
Synonyms
NYREN8; PPP2R3L; PPP2R3LY; PR48; PR70
Gene ID
28227
UniProt
Q9Y5P8
Accession Number mRNA
NM_013239
Chromosomal Location
X; Y
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome, Phosphatase
Molecular Weight
64.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PPP2R3B
Species
Human
Protein ID
NP_037371
Overview
Purified recombinant protein of Human protein phosphatase 2, regulatory subunit B'', beta (PPP2R3B), full length, with N-terminal HIS tag, expressed in E.coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/28227
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y5P8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_013239
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_037371
Curated Selection
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