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PPP2R3B (NM_013239) Human Recombinant Protein

Product Specifications

Background

Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. [provided by RefSeq, Apr 2010]

Synonyms

NYREN8; PPP2R3L; PPP2R3LY; PR48; PR70

Gene ID

28227

UniProt

Q9Y5P8

Accession Number mRNA

NM_013239

Chromosomal Location

X; Y

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Druggable Genome, Phosphatase

Molecular Weight

64.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PPP2R3B

Species

Human

Protein ID

NP_037371

Overview

Purified recombinant protein of Human protein phosphatase 2, regulatory subunit B'', beta (PPP2R3B), full length, with N-terminal HIS tag, expressed in E.coli, 50ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/28227

Uniprot URL

https://www.uniprot.org/uniprot/Q9Y5P8

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_013239

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_037371

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