Rho GTPase activating protein 24 (ARHGAP24) (NM_001042669) Human Recombinant Protein
Product Specifications
Background
This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Overview
Purified recombinant protein of Human Rho GTPase activating protein 24 (ARHGAP24), transcript variant 3, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
FILGAP; p73; p73RhoGAP; RC-GAP72; RCGAP72
Gene ID
83478
UniProt
Q8N264
Accession Number mRNA
NM_001042669
Chromosomal Location
4q21.23-q21.3
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Molecular Weight
73.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ARHGAP24
Species
Human
Protein ID
NP_001036134
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/83478
Uniprot URL
https://www.uniprot.org/uniprot/Q8N264
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001042669
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001036134
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