Dnmt2 (TRDMT1) (NM_004412) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA- (cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa. [provided by RefSeq, Jun 2010]
Synonyms
DMNT2; DNMT2; MHSAIIP; PUMET; RNMT1
Gene ID
1787
UniProt
O14717, Q6ICS7
Accession Number mRNA
NM_004412
Chromosomal Location
10p13
Expression System
E. coli
Tag
N-His
Related Pathways
Cysteine and methionine metabolism, Metabolic pathways
Field of Research
Cysteine and methionine metabolism, Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome
Molecular Weight
44.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TRDMT1
Species
Human
Protein ID
NP_004403
Overview
Purified recombinant protein of Human tRNA aspartic acid methyltransferase 1 (TRDMT1), full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1787
Uniprot URL
https://www.uniprot.org/uniprot/O14717
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004412
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004403
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