Dnmt2 (TRDMT1) (NM_004412) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA- (cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa. [provided by RefSeq, Jun 2010]

Overview

Purified recombinant protein of Human tRNA aspartic acid methyltransferase 1 (TRDMT1), full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

DMNT2; DNMT2; MHSAIIP; PUMET; RNMT1

Gene ID

1787

UniProt

O14717, Q6ICS7

Accession Number mRNA

NM_004412

Chromosomal Location

10p13

Expression System

E. coli

Tag

N-His

Related Pathways

Cysteine and methionine metabolism, Metabolic pathways

Field of Research

Cysteine and methionine metabolism, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Druggable Genome

Molecular Weight

44.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.