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Glutathione S Transferase theta 1 (GSTT1) (NM_000853) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT1 and GSTT2/GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis. The GSTT1 gene is haplotype-specific and is absent from 38% of the population. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Synonyms

Glutathione S-transferase theta 1

Gene ID

2952

UniProt

P30711

Accession Number mRNA

NM_000853

Chromosomal Location

22q11.23

Expression System

E. coli

Tag

N-His

Related Pathways

Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450

Field of Research

Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Molecular Weight

27.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

GSTT1

Species

Human

Protein ID

NP_000844

Overview

Purified recombinant protein of Human glutathione S-transferase theta 1 (GSTT1), full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2952

Uniprot URL

https://www.uniprot.org/uniprot/P30711

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_000853

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_000844

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