ADA2a (TADA2A) (NM_133439) Human Recombinant Protein
Product Specifications
Background
Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2009]
Synonyms
ADA2; ADA2A; hADA2; KL04P; TADA2L
Gene ID
6871
UniProt
O75478, A0A087WWR4
Accession Number mRNA
NM_133439
Chromosomal Location
17q12
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Transcription Factors
Molecular Weight
35.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TADA2A
Species
Human
Protein ID
NP_597683
Overview
Purified recombinant protein of Human transcriptional adaptor 2A (TADA2A), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6871
Uniprot URL
https://www.uniprot.org/uniprot/O75478
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_133439
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_597683
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