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ADA2a (TADA2A) (NM_133439) Human Recombinant Protein

Product Specifications

Background

Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2009]

Overview

Purified recombinant protein of Human transcriptional adaptor 2A (TADA2A), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

ADA2; ADA2A; hADA2; KL04P; TADA2L

Gene ID

6871

UniProt

O75478, A0A087WWR4

Accession Number mRNA

NM_133439

Chromosomal Location

17q12

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Transcription Factors

Molecular Weight

35.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

TADA2A

Species

Human

Protein ID

NP_597683

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6871

Uniprot URL

https://www.uniprot.org/uniprot/O75478

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_133439

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_597683

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