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Pleiotrophin (PTN) (NM_002825) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a secreted heparin-binding growth factor. The protein has significant roles in cell growth and survival, cell migration, angiogenesis and tumorigenesis. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]

Synonyms

HARP; HB-GAM; HBBM; HBGF-8; HBGF8; HBNF; HBNF-1; NEGF1; OSF-1

Gene ID

5764

UniProt

P21246, A0A024R778

Accession Number mRNA

NM_002825

Chromosomal Location

7q33

Expression System

E. coli

Tag

N-GST and C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Druggable Genome, Phosphatase, Secreted Protein, Transmembrane

Molecular Weight

44.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PTN

Species

Human

Protein ID

NP_002816

Overview

Purified recombinant protein of Human pleiotrophin (PTN), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/5764

Uniprot URL

https://www.uniprot.org/uniprot/P21246

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002825

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002816

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