RASGRP3 (NM_170672) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers. [provided by RefSeq, Mar 2017]
Overview
Purified recombinant protein of Human RAS guanyl releasing protein 3 (calcium and DAG-regulated) (RASGRP3), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Synonyms
GRP3
Gene ID
25780
UniProt
Q8IV61
Accession Number mRNA
NM_170672
Chromosomal Location
2p22.3
Expression System
E. coli
Tag
N-GST and C-His
Related Pathways
B cell receptor signaling pathway, MAPK signaling pathway
Field of Research
B cell receptor signaling pathway, MAPK signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Molecular Weight
104.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RASGRP3
Species
Human
Protein ID
NP_733772
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/25780
Uniprot URL
https://www.uniprot.org/uniprot/Q8IV61
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_170672
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_733772
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