Kallikrein 1 (KLK1) (NM_002257) Human Recombinant Protein

Product Specifications

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human kallikrein 1 (KLK1), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Synonyms

HK1; Klk6; KLKR

Gene ID

3816

UniProt

P06870, A0A1R3UCD2

Accession Number mRNA

NM_002257

Chromosomal Location

19q13.33

Expression System

E. coli

Tag

N-GST and C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Druggable Genome, Protease

Molecular Weight

53 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.