Kallikrein 1 (KLK1) (NM_002257) Human Recombinant Protein
Product Specifications
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. [provided by RefSeq, Jul 2008]
Synonyms
HK1; Klk6; KLKR
Gene ID
3816
UniProt
P06870, A0A1R3UCD2
Accession Number mRNA
NM_002257
Chromosomal Location
19q13.33
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome, Protease
Molecular Weight
53 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KLK1
Species
Human
Protein ID
NP_002248
Overview
Purified recombinant protein of Human kallikrein 1 (KLK1), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3816
Uniprot URL
https://www.uniprot.org/uniprot/P06870
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002257
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002248
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