Kallikrein 14 (KLK14) (NM_022046) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the kallikrein subfamily of serine proteases that have diverse physiological functions such as regulation of blood pressure and desquamation. The altered expression of this gene is implicated in the progression of different cancers including breast and prostate tumors. The encoded protein is a precursor that is proteolytically processed to generate the functional enzyme. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Synonyms
KLK-L6
Gene ID
43847
UniProt
Q9P0G3, A0A1R3UHJ7, A0A024R4M6
Accession Number mRNA
NM_022046
Chromosomal Location
19q13.41
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Function
Druggable Genome, Protease, Secreted Protein
Molecular Weight
28.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KLK14
Species
Human
Protein ID
NP_071329
Overview
Purified recombinant protein of Human kallikrein-related peptidase 14 (KLK14), full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/43847
Uniprot URL
https://www.uniprot.org/uniprot/Q9P0G3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_022046
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_071329
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