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Kallikrein 14 (KLK14) (NM_022046) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the kallikrein subfamily of serine proteases that have diverse physiological functions such as regulation of blood pressure and desquamation. The altered expression of this gene is implicated in the progression of different cancers including breast and prostate tumors. The encoded protein is a precursor that is proteolytically processed to generate the functional enzyme. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

Overview

Purified recombinant protein of Human kallikrein-related peptidase 14 (KLK14), full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

KLK-L6

Gene ID

43847

UniProt

Q9P0G3, A0A1R3UHJ7, A0A024R4M6

Accession Number mRNA

NM_022046

Chromosomal Location

19q13.41

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Function

Druggable Genome, Protease, Secreted Protein

Molecular Weight

28.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

KLK14

Species

Human

Protein ID

NP_071329

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/43847

Uniprot URL

https://www.uniprot.org/uniprot/Q9P0G3

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_022046

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_071329

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