Cytokeratin 3 (KRT3) (NM_057088) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
Overview
Purified recombinant protein of Human keratin 3 (KRT3), full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
CK3; K3; MECD2
Gene ID
3850
UniProt
P12035
Accession Number mRNA
NM_057088
Chromosomal Location
12q13.13
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Molecular Weight
64.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KRT3
Species
Human
Protein ID
NP_476429
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3850
Uniprot URL
https://www.uniprot.org/uniprot/P12035
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_057088
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_476429
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