USP22 (NM_015276) Human Recombinant Protein

Product Specifications

Background

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Human ubiquitin specific peptidase 22 (USP22), full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

USP3L

Gene ID

23326

UniProt

Q9UPT9

Accession Number mRNA

NM_015276

Chromosomal Location

17p11.2

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Function

Protease

Molecular Weight

59.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.