C1QC (NM_001114101) Human Recombinant Protein
Product Specifications
Background
This gene encodes the C-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. [provided by RefSeq, Dec 2016]
Overview
Purified recombinant protein of Human complement component 1, q subcomponent, C chain (C1QC), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
C1Q-C; C1QG
Gene ID
714
UniProt
P02747, A0A024RAA7
Accession Number mRNA
NM_001114101
Chromosomal Location
1p36.12
Expression System
E. coli
Tag
N-His
Related Pathways
Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus
Field of Research
Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Function
Secreted Protein
Molecular Weight
22.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
C1QC
Species
Human
Protein ID
NP_001107573
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/714
Uniprot URL
https://www.uniprot.org/uniprot/P02747
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001114101
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001107573
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