COX7B (NM_001866) Human Recombinant Protein
Product Specifications
Background
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIb, which is highly similar to bovine COX VIIb protein and is found in all tissues. This gene may have several pseudogenes on chromosomes 1, 2, 20 and 22. [provided by RefSeq, Jun 2011]
Synonyms
APLCC; LSDMCA2
Gene ID
1349
UniProt
P24311
Accession Number mRNA
NM_001866
Chromosomal Location
Xq21.1
Expression System
E. coli
Tag
N-His
Related Pathways
Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease
Field of Research
Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Molecular Weight
6.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
COX7B
Species
Human
Protein ID
NP_001857
Overview
Purified recombinant protein of Human cytochrome c oxidase subunit VIIb (COX7B), nuclear gene encoding mitochondrial protein, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1349
Uniprot URL
https://www.uniprot.org/uniprot/P24311
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001866
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001857
Curated Selection
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