DEF6 (NM_022047) Human Recombinant Protein
Product Specifications
Background
DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]) .[supplied by OMIM, Mar 2008]
Synonyms
IBP; SLAT; SWAP70L
Gene ID
50619
UniProt
Q9H4E7
Accession Number mRNA
NM_022047
Chromosomal Location
6p21.31
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Function
Druggable Genome
Molecular Weight
73.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DEF6
Species
Human
Protein ID
NP_071330
Overview
Purified recombinant protein of Human differentially expressed in FDCP 6 homolog (mouse) (DEF6), full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/50619
Uniprot URL
https://www.uniprot.org/uniprot/Q9H4E7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_022047
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_071330
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