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AGXT2 (NM_031900) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. It is an important regulator of methylarginines and is involved in the control of blood pressure in kidney. Polymorphisms in this gene affect methylarginine and beta-aminoisobutyrate metabolism, and are associated with carotid atherosclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Overview

Purified recombinant protein of Human alanine--glyoxylate aminotransferase 2 (AGXT2), nuclear gene encoding mitochondrial protein, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

AGT2; BAIBA; DAIBAT

Gene ID

64902

UniProt

Q9BYV1

Accession Number mRNA

NM_031900

Chromosomal Location

5p13.2

Expression System

E. coli

Tag

N-His

Related Pathways

Alanine, aspartate and glutamate metabolism

Field of Research

Alanine, aspartate and glutamate metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Function

Druggable Genome

Molecular Weight

52.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

AGXT2

Species

Human

Protein ID

NP_114106

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/64902

Uniprot URL

https://www.uniprot.org/uniprot/Q9BYV1

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_031900

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_114106

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