Histidase (HAL) (NM_002108) Human Recombinant Protein
Product Specifications
Background
Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Overview
Purified recombinant protein of Human histidine ammonia-lyase (HAL), full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
HIS; HSTD
Gene ID
3034
UniProt
P42357
Accession Number mRNA
NM_002108
Chromosomal Location
12q23.1
Expression System
E. coli
Tag
N-His
Related Pathways
Histidine metabolism, Metabolic pathways, Nitrogen metabolism
Field of Research
Histidine metabolism, Metabolic pathways, Nitrogen metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Function
Druggable Genome
Molecular Weight
72.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HAL
Species
Human
Protein ID
NP_002099
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3034
Uniprot URL
https://www.uniprot.org/uniprot/P42357
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002108
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002099
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