EOMES (NM_005442) Human Recombinant Protein
Product Specifications
Background
This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Overview
Purified recombinant protein of Human eomesodermin (EOMES), full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
TBR2
Gene ID
8320
UniProt
O95936, B7Z4K0
Accession Number mRNA
NM_005442
Chromosomal Location
3p24.1
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Function
Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors
Molecular Weight
72.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
EOMES
Species
Human
Protein ID
NP_005433
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8320
Uniprot URL
https://www.uniprot.org/uniprot/O95936
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005442
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005433
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