EOMES (NM_005442) Human Recombinant Protein

Product Specifications

Background

This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Overview

Purified recombinant protein of Human eomesodermin (EOMES), full length, with N-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

TBR2

Gene ID

8320

UniProt

O95936, B7Z4K0

Accession Number mRNA

NM_005442

Chromosomal Location

3p24.1

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Function

Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors

Molecular Weight

72.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.