ATG16L1 (NM_198890) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10) . Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]
Overview
Purified recombinant protein of Human ATG16 autophagy related 16-like 1 (S. cerevisiae) (ATG16L1), transcript variant 3, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
APG16L; ATG16A; ATG16L; IBD10; WDR30
Gene ID
55054
UniProt
Q676U5
Accession Number mRNA
NM_198890
Chromosomal Location
2q37.1
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Molecular Weight
49.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ATG16L1
Species
Human
Protein ID
NP_942593
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55054
Uniprot URL
https://www.uniprot.org/uniprot/Q676U5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_198890
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_942593
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