XAF1 (NM_017523) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

Overview

Purified recombinant protein of Human XIAP associated factor 1 (XAF1), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Synonyms

BIRC4BP; HSXIAPAF1; XIAPAF1

Gene ID

54739

UniProt

Q6GPH4

Accession Number mRNA

NM_017523

Chromosomal Location

17p13.1

Expression System

E. coli

Tag

N-GST and C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.

Molecular Weight

62.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.