XAF1 (NM_017523) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
Synonyms
BIRC4BP; HSXIAPAF1; XIAPAF1
Gene ID
54739
UniProt
Q6GPH4
Accession Number mRNA
NM_017523
Chromosomal Location
17p13.1
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.
Molecular Weight
62.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
XAF1
Species
Human
Protein ID
NP_059993
Overview
Purified recombinant protein of Human XIAP associated factor 1 (XAF1), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/54739
Uniprot URL
https://www.uniprot.org/uniprot/Q6GPH4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_017523
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_059993
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