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PITX3 (NM_005029) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. This protein is involved in lens formation during eye development. Mutations of this gene have been associated with anterior segment mesenchymal dysgenesis and congenital cataracts. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human paired-like homeodomain 3 (PITX3), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Synonyms

ASGD1; ASMD; ASOD; CTPP4; CTRCT11; PTX3

Gene ID

5309

UniProt

O75364

Accession Number mRNA

NM_005029

Chromosomal Location

10q24.32

Expression System

E. coli

Tag

N-GST and C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.

Function

Druggable Genome, Transcription Factors

Molecular Weight

57.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PITX3

Species

Human

Protein ID

NP_005020

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/5309

Uniprot URL

https://www.uniprot.org/uniprot/O75364

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005029

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005020

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