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MTCH2 (NM_014342) Human Recombinant Protein

Selected Variant

PH31128E6

Size: 50 µg

Product Specifications

Background

This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target that can produce two isoforms from the same mRNA by use of alternative in-frame translation termination codons. [provided by RefSeq, Dec 2017]

Overview

Purified recombinant protein of Human mitochondrial carrier 2 (MTCH2), nuclear gene encoding mitochondrial protein, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Synonyms

HSPC032; MIMP; SLC25A50

Gene ID

23788

UniProt

Q9Y6C9

Accession Number mRNA

NM_014342

Chromosomal Location

11p11.2

Expression System

E. coli

Tag

N-GST and C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.

Molecular Weight

59.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

MTCH2

Species

Human

Protein ID

NP_055157

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/23788

Uniprot URL

https://www.uniprot.org/uniprot/Q9Y6C9

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_014342

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_055157

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