MPG (NM_001015054) Human Recombinant Protein
Product Specifications
Background
Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Human N-methylpurine-DNA glycosylase (MPG), transcript variant 3, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Synonyms
AAG; ADPG; anpg; APNG; CRA36.1; MDG; Mid1; PIG11; PIG16
Gene ID
4350
UniProt
P29372
Accession Number mRNA
NM_001015054
Chromosomal Location
16p13.3
Expression System
E. coli
Tag
N-GST and C-His
Related Pathways
Base excision repair
Field of Research
Base excision repair
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.
Function
Druggable Genome, Transmembrane
Molecular Weight
58.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MPG
Species
Human
Protein ID
NP_001015054
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4350
Uniprot URL
https://www.uniprot.org/uniprot/P29372
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001015054
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001015054
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