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MPG (NM_001015054) Human Recombinant Protein

Product Specifications

Background

Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Human N-methylpurine-DNA glycosylase (MPG), transcript variant 3, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Synonyms

AAG; ADPG; anpg; APNG; CRA36.1; MDG; Mid1; PIG11; PIG16

Gene ID

4350

UniProt

P29372

Accession Number mRNA

NM_001015054

Chromosomal Location

16p13.3

Expression System

E. coli

Tag

N-GST and C-His

Related Pathways

Base excision repair

Field of Research

Base excision repair

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.

Function

Druggable Genome, Transmembrane

Molecular Weight

58.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

MPG

Species

Human

Protein ID

NP_001015054

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/4350

Uniprot URL

https://www.uniprot.org/uniprot/P29372

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001015054

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001015054

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