HEY1 (NM_012258) Human Recombinant Protein
Selected Variant
PH31091E6
Size: 50 µg
Product Specifications
Background
This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH) -type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Overview
Purified recombinant protein of Human hairy/enhancer-of-split related with YRPW motif 1 (HEY1), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Synonyms
BHLHb31; CHF2; HERP2; HESR1; hHRT1; HRT-1; NERP2; OAF1
Gene ID
23462
UniProt
Q9Y5J3
Accession Number mRNA
NM_012258
Chromosomal Location
8q21.13
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.
Function
Druggable Genome, Transcription Factors
Molecular Weight
58.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HEY1
Species
Human
Protein ID
NP_036390
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/23462
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y5J3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_012258
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_036390
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