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ICAM4 (NM_001544) Human Recombinant Protein

Product Specifications

Background

This gene encodes the Landsteiner-Wiener (LW) blood group antigen (s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW (A) /LW (B) blood group antigens is a single aa variation at position 100; Gln-100=LW (A) and Arg-100=LW (B) . Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) (ICAM4), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Synonyms

CD242; LW

Gene ID

3386

UniProt

Q14773

Accession Number mRNA

NM_001544

Chromosomal Location

19p13.2

Expression System

E. coli

Tag

N-GST and C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.

Function

Secreted Protein, Transmembrane

Molecular Weight

55.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ICAM4

Species

Human

Protein ID

NP_001535

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3386

Uniprot URL

https://www.uniprot.org/uniprot/Q14773

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001544

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001535

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