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FBXL5 (NM_033535) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2010]

Overview

Purified recombinant protein of Human F-box and leucine-rich repeat protein 5 (FBXL5), transcript variant 2, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

F-box and leucine-rich repeat protein 5; F-box protein FBL5; FBL4; FBL5; FLR1

Gene ID

26234

UniProt

Q9UKA1

Accession Number mRNA

NM_033535

Chromosomal Location

4p15.32

Expression System

E. coli

Tag

N-GST and C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.

Function

Druggable Genome

Molecular Weight

91.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FBXL5

Species

Human

Protein ID

NP_277077

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/26234

Uniprot URL

https://www.uniprot.org/uniprot/Q9UKA1

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_033535

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_277077

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