FBXL5 (NM_033535) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2010]
Overview
Purified recombinant protein of Human F-box and leucine-rich repeat protein 5 (FBXL5), transcript variant 2, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
F-box and leucine-rich repeat protein 5; F-box protein FBL5; FBL4; FBL5; FLR1
Gene ID
26234
UniProt
Q9UKA1
Accession Number mRNA
NM_033535
Chromosomal Location
4p15.32
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.
Function
Druggable Genome
Molecular Weight
91.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FBXL5
Species
Human
Protein ID
NP_277077
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/26234
Uniprot URL
https://www.uniprot.org/uniprot/Q9UKA1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_033535
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_277077
Curated Selection
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