Cyclin C (CCNC) (NM_001013399) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Overview
Purified recombinant protein of Human cyclin C (CCNC), transcript variant 2, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
CycC; hSRB11; SRB11
Gene ID
892
UniProt
P24863, Q7Z4L3
Accession Number mRNA
NM_001013399
Chromosomal Location
6q16.2
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.
Function
Druggable Genome, Transcription Factors
Molecular Weight
50.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CCNC
Species
Human
Protein ID
NP_001013417
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/892
Uniprot URL
https://www.uniprot.org/uniprot/P24863
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001013399
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001013417
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