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RPL3 (NM_000967) Human Recombinant Protein

Product Specifications

Background

Ribosomes, the complexes that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation. This gene is co-transcribed with several small nucleolar RNA genes, which are located in several of this gene's introns. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Synonyms

ASC-1; L3; TARBP-B

Gene ID

6122

UniProt

P39023

Accession Number mRNA

NM_000967

Chromosomal Location

22q13.1

Expression System

E. coli

Tag

N-GST and C-His

Related Pathways

Ribosome

Field of Research

Ribosome

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.

Molecular Weight

73.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

RPL3

Species

Human

Protein ID

NP_000958

Overview

Purified recombinant protein of Human ribosomal protein L3 (RPL3), transcript variant 1, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6122

Uniprot URL

https://www.uniprot.org/uniprot/P39023

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_000967

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_000958

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