EID3 (NM_001008394) Human Recombinant Protein
Product Specifications
Background
Tissue-specific component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Human EP300 interacting inhibitor of differentiation 3 (EID3), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
NS4EB; NSE4B; NSMCE4B
Gene ID
493861
UniProt
Q8N140, A0A140VJI9
Accession Number mRNA
NM_001008394
Chromosomal Location
12q23.3
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.
Molecular Weight
66 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
EID3
Species
Human
Protein ID
NP_001008395
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/493861
Uniprot URL
https://www.uniprot.org/uniprot/Q8N140
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001008394
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001008395
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