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EID3 (NM_001008394) Human Recombinant Protein

Product Specifications

Background

Tissue-specific component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Human EP300 interacting inhibitor of differentiation 3 (EID3), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug

Synonyms

NS4EB; NSE4B; NSMCE4B

Gene ID

493861

UniProt

Q8N140, A0A140VJI9

Accession Number mRNA

NM_001008394

Chromosomal Location

12q23.3

Expression System

E. coli

Tag

N-GST and C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.

Molecular Weight

66 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

EID3

Species

Human

Protein ID

NP_001008395

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/493861

Uniprot URL

https://www.uniprot.org/uniprot/Q8N140

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001008394

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001008395

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